A glucose-responsive controlled release of insulin system based on enzyme multilayers-coated mesoporous silica particles.
نویسندگان
چکیده
A novel glucose-responsive controlled release of insulin system is constructed through coating enzyme multilayers on mesoporous silica particles (MSPs). The MSPs serve as the drug reservoir, and the enzyme multilayers cross-linked with glutaraldehyde act as a valve to control the release of insulin in response to the external glucose level.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 33 شماره
صفحات -
تاریخ انتشار 2011